Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups
Description
Although the SARS-CoV-2 pandemic has ended, multiple sporadic cases still exist, posing a request for more antivirals. The main protease (M^(pro)) of SARS-CoV-2, a key enzyme for viral replication, is an attractive target for drug development. Here