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PubMed COVID-19 Clinical Care

54071 - 54080 of 57753 results found

Coronaviruses Use ACE2 Monomers as Entry-Receptors

Date
Monday, March 27, 2023 - 4:00 AM
Description
The angiotensin-converting enzyme 2 (ACE2) has been identified as entry receptor on cells enabling binding and infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via trimeric spike (S) proteins protruding from the viral

Recent advances in critical care: Part II

Date
Monday, March 27, 2023 - 4:00 AM
Description
With the increasing number of critically ill patients being admitted to intensive care units (ICUs), newer techniques and treatment modalities continue to evolve for their adequate management. Thus, it has become imperative to understand existing

Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors

Date
Monday, March 27, 2023 - 4:00 AM
Description
A naturally inspired chemical library of 25 molecules was synthesised guided by 3-D dimensionality and natural product likeness factors to explore a new chemical space. The synthesised chemical library, consisting of fused-bridged dodecahydro-2a,6