Loading icon
Press enter or spacebar to select a desired language.
Research
Press enter or spacebar to select a desired language.

PubMed COVID-19 Clinical Care

53251 - 53260 of 57753 results found

Rapid resistance profiling of SARS-CoV-2 protease inhibitors

Date
Thursday, March 30, 2023 - 4:00 AM
Description
Resistance to nirmatrelvir (Paxlovid) has been shown by multiple groups and may already exist in clinical SARS-CoV-2 isolates. Here a panel of SARS-CoV-2 main protease (Mpro) variants and a robust cell-based assay are used to compare the resistance