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PubMed COVID-19 Clinical Care

52821 - 52830 of 57753 results found

All-atom simulations of the trimeric spike protein of SARS-CoV-2 in aqueous medium: Nature of interactions, conformational stability and free energy diagrams for conformational transition of the protein

Date
Friday, March 31, 2023 - 4:00 AM
Description
The spike protein of SARS-CoV-2 exists in two major conformational states, namely the 'open' and 'closed' states which are also known as the 'up' and 'down' states, respectively. In its open state, the receptor binding domain (RBD) of the protein is

Biomimetic SARS-CoV-2 Spike Protein Nanoparticles

Date
Friday, March 31, 2023 - 4:00 AM
Description
COVID-19 is an infectious respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus contains a crucial coat protein that engages with target cells via a receptor binding domain (RBD) on its spike