PubMed COVID-19 Clinical Care
4371 - 4380 of 57753 results found
Clinician and patient views on janus kinase inhibitors in the treatment of inflammatory arthritis: a mixed methods study
Description
CONCLUSION: JAKi are an effective treatment option for IA and are liked by patients. The COVID-19 pandemic appears to have impacted their prescription favourably. However, clinicians have safety concerns over JAKi use. Any decision to go on a JAKi
Socioeconomic impacts of airborne and droplet-borne infectious diseases on industries: a systematic review
Description
CONCLUSIONS: Evidence suggests that airborne and droplet-borne infectious diseases have inflicted severe socioeconomic costs on regional and global industries. Further research is needed to better understand their long-term socioeconomic impacts to
Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants
Description
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted in distinct lineages with enhanced transmissibility called variants of concern (VOCs). Omicron is the first VOC to evolve distinct globally dominant subvariants
How manufacturing won or lost the COVID-19 vaccine race
Description
The development of vaccines for COVID-19 occurred at an unprecedented pace, and 32 vaccines using a broad range of technologies had received authorization for use on an emergency basis by the end of 2021, from either a national regulatory authority
Effects of fear of COVID-19 on older volunteers' willingness to continue their activities: REPRINTS cohort study
Description
CONCLUSIONS: Our results suggest that the willingness of older adults to continue volunteer activities during the COVID-19 pandemic is influenced by their volunteer orientation and is not affected by their fear of COVID-19. Geriatr Gerontol Int 2024
Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1
Description
SARS-CoV-2 rapidly mutates and acquires resistance to neutralizing antibodies. We report an in-silico-designed antibody that restores the neutralizing activity of a neutralizing antibody. Our previously generated antibody, UT28K, exhibited broad
Practical approach to a patient with a fever after travelling to the tropics
Description
By 2030, an estimated two billion international tourist trips are expected annually worldwide, with Poland as an important contributor. Illness rates among returnees from developing regions hover between 43-79%. Properly diagnosing fever in these
Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL
Description
Platform trials bring the promise of making clinical research more efficient and more patient centric. While their use has become more widespread, including their prominent role during the COVID-19 pandemic response, broader adoption of platform
