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PubMed COVID-19 Clinical Care

29881 - 29890 of 57753 results found

Evolutionary safety of lethal mutagenesis driven by antiviral treatment

Date
Tuesday, August 08, 2023 - 4:00 AM
Description
Nucleoside analogs are a major class of antiviral drugs. Some act by increasing the viral mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however, may lead to an evolutionary safety concern. We define evolutionary

Comparison of ordinary reverse transcription real-time polymerase chain reaction (qRT-PCR) with a newly developed one-step single-tube nested real-time RT-PCR (OSN-qRT-PCR) for sensitive detection of SARS-CoV-2 in wastewater

Date
Tuesday, August 08, 2023 - 4:00 AM
Description
Wastewater monitoring has proven to be an important approach to detecting and controlling the development of the SARS-CoV-2 pandemic. Various tests based on reverse transcription real-time PCR (qRT-PCR) have been developed and used for the detection