PubMed COVID-19 Clinical Care

Varying (preferred) levels of involvement in treatment decision-making in the intensive care unit before and during the COVID-19 pandemic: a mixed-methods study among relatives

Monday, February 12, 2024 - 4:00 AM

CONCLUSIONS: As treatment alignment with a patient's values and preferences and accordance between preferred and actual involvement in decision-making is very important, we suggest that the treatment decision-making process should start with

Mental Health Status by Race, Ethnicity and Socioeconomic Status among Young Adults in Texas during COVID-19

Monday, February 12, 2024 - 4:00 AM

CONCLUSION: Low SES was persistently related to poor mental health. Lower odds of symptoms of anxiety and depression among non-Hispanic Black young adults may reflect the 'mental health paradox'. Overall, mental health policies should prioritize

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea

Monday, February 12, 2024 - 4:00 AM

Cognitive impairment, depression and (mental) fatigue represent the most frequent neuropsychiatric symptoms of the post-COVID syndrome. Neuroinflammation, oxidative stress and mitochondrial dysfunction have been identified as common

Postpartum pharmacologic thromboprophylaxis and complications in a US cohort

Monday, February 12, 2024 - 4:00 AM

CONCLUSION: Approximately 1 in 10 patients received postpartum pharmacologic thromboprophylaxis in this US cohort. Rates of prophylaxis varied widely by institution. Cesarean delivery, hysterectomy, and obesity were predominant factors associated

Mechanisms underlying exercise intolerance in long COVID: An accumulation of multisystem dysfunction

Monday, February 12, 2024 - 4:00 AM

The pathogenesis of exercise intolerance and persistent fatigue which can follow an infection with the SARS-CoV-2 virus ("long COVID") is not fully understood. Cases were recruited from a long COVID clinic (N = 32; 44 ± 12 years; 10 (31%) men), and

Re: 'COVID-19 mortality among selective serotonin reuptake inhibitor users' by Stauning et al

Monday, February 12, 2024 - 4:00 AM

No abstract

Features of Cytokine and VEGFA Gene Expression Modified with SARS-CoV-2 Virus in an In Vitro Experiment (Using the Example of the SARS-CoV-2 Vaccine Antigen)

Sunday, February 11, 2024 - 4:00 AM

The influence of SARS-CoV-2 antigen on the cytokine-producing function of immune cells was studied. We observed suppression of the production of proinflammatory cytokines by 11-46% relative to the spontaneous level under the influence of SARS-CoV-2

Impact of influenza vaccination history in the clinical course of older adults hospitalized with COVID-19

Sunday, February 11, 2024 - 4:00 AM

CONCLUSION: In this study, a history of influenza vaccination in older adults with SARS-CoV-2 infection was related to lower in-hospital mortality.

fRace and Ethnicity Research in Cardiovascular Disease in Canada: Challenges and Opportunities

Sunday, February 11, 2024 - 4:00 AM

Even though Canada is one of the most culturally diverse countries in the world, offering universal healthcare to all its citizens, the recent COVID-19 pandemic has exposed significant health inequities in our healthcare system. We continue to face

A validated LC-MS/MS method for determination of six Anti-SARS-CoV-2 drugs in plasma and its application for a pharmacokinetic study in rats

Sunday, February 11, 2024 - 4:00 AM

Antiviral treatment for COVID-19 is considered an effective tool in reducing the rate of severe cases and deaths. As of June 2023, a total of six small molecule antiviral drugs have been conditionally approved for marketing by the National Medical