Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors
Description
A critical step for SARS-CoV-2 assembly and maturation involves the autoactivation of the main protease (MPro^(WT)) from precursor polyproteins. Upon expression, a model precursor of MPro^(WT) mediates its own release at its termini rapidly to yield
