PubMed COVID-19 Clinical Care

Artificial neural network based prediction of the lung tissue involvement as an independent in-hospital mortality and mechanical ventilation risk factor in COVID-19

Tuesday, May 23, 2023 - 4:00 AM

CONCLUSIONS: ANN-based lung tissue involvement is the strongest predictor of unfavorable outcomes in COVID-19 and represents a valuable support tool for clinical decisions.

Extension of Lung Damage at Chest Computed Tomography in Severely Ill COVID-19 Patients Treated with Interleukin-6 Receptor Blockers Correlates with Inflammatory Cytokines Production and Prognosis

Tuesday, May 23, 2023 - 4:00 AM

Elevated inflammatory markers are associated with severe coronavirus disease 2019 (COVID-19), and some patients benefit from Interleukin (IL)-6 pathway inhibitors. Different chest computed tomography (CT) scoring systems have shown a prognostic value

Incidence and Risk Factors of the COVID-19 Pandemic: An Epidemiological Approach

Tuesday, May 23, 2023 - 4:00 AM

After three years of the COVID-19 pandemic, it is certain that the SARS-CoV-2 virus has been a turning point for humanity in both developed and developing countries [...].

Invasive Pulmonary Aspergillosis in Coronavirus Disease 2019 Patients Lights and Shadows in the Current Landscape

Tuesday, May 23, 2023 - 4:00 AM

Invasive pulmonary aspergillosis (IPA) presents a known risk to critically ill patients with SARS-CoV-2; quantifying the global burden of IPA in SARS-CoV-2 is extremely challenging. The true incidence of COVID-19-associated pulmonary aspergillosis

Rational Design of Covalent Kinase Inhibitors by an Integrated Computational Workflow (Kin-Cov)

Tuesday, May 23, 2023 - 4:00 AM

Covalent kinase inhibitors (CKIs) hold great promise for drug development. However, examples of computationally guided design of CKIs are still scarce. Here, we present an integrated computational workflow (Kin-Cov) for rational design of CKIs. The

Resiliency and vulnerability in early grades writing performance during the COVID-19 pandemic

Tuesday, May 23, 2023 - 4:00 AM

To explore potential pandemic-related learning gaps on expressive writing skills, predominantly Hispanic (≈50%) and White (≈30%) primary-grade students responded to grade-specific writing prompts in the fall semesters before and after school closures

Essential Oil Derived from Underutilized Plants Cymbopogon khasianus Poses Diverse Biological Activities against "Aspergillosis" and "Mucormycosis"

Tuesday, May 23, 2023 - 4:00 AM

Palmrosa essential oil (PEO) from Cymbopogon khasianus, is used as complementary and traditional medicine worldwide. The present study aimed at compositional profiling of PEO and molecular docking of PEO bioactive compound geraniol against fungal

Individual-Community Misalignment in Partisan Identity Predicts Distancing From Norms During the COVID-19 Pandemic

Tuesday, May 23, 2023 - 4:00 AM

This study investigated whether misalignment between an individual and their community in partisan identity predicted psychological and behavioral distancing from local COVID-19 norms. A nationally representative sample of Republicans and Democrats

Loneliness and Mental Health in Response to Early and Late COVID-19 Outbreak: A Cross-Sectional Study of Czech Adults Aged 50 and Over

Tuesday, May 23, 2023 - 4:00 AM

The unpredictable spread of the COVID-19 pandemic, national lockdowns, and public health measures implemented in the Czech Republic had a negative effect on older adults' mental health and loneliness. The 2,631 older adults in 2020 and 2,083 older

AOA Critical Issues Symposium: Leadership and Education During and After COVID-19: Back to the Future or a New Normal

Tuesday, May 23, 2023 - 4:00 AM

The devastating impact of COVID-19 has reshaped how we lead and train our future surgeons in the field of orthopaedics. Overnight, leaders in our field had to dramatically shift their mindset to continue to lead a hospital, department, journal, or