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PubMed COVID-19 Clinical Care

25191 - 25200 of 57753 results found

SARS-CoV-2 Nsp8 N-terminal domain folds autonomously and binds dsRNA

Date
Monday, September 04, 2023 - 4:00 AM
Description
The SARS-CoV-2 Nsp8 protein is a critical component of the RNA replicase, as its N-terminal domain (NTD) anchors Nsp12, the RNA, and Nsp13. Whereas its C-terminal domain (CTD) structure is well resolved, there is an open debate regarding the