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PubMed COVID-19 Clinical Care

21841 - 21850 of 57753 results found

Distinguishing features of Long COVID identified through immune profiling

Date
Monday, September 25, 2023 - 4:00 AM
Description
Post-acute infection syndromes (PAIS) may develop after acute viral disease¹. Infection with SARS-CoV-2 can result in the development of a PAIS known as "Long COVID" (LC). Individuals with LC frequently report unremitting fatigue, post-exertional

Examining Functional Linkages Between Conformational Dynamics, Protein Stability and Evolution of Cryptic Binding Pockets in the SARS-CoV-2 Omicron Spike Complexes with the ACE2 Host Receptor: Recombinant Omicron Variants Mediate Variability of Conserv...

Date
Monday, September 25, 2023 - 4:00 AM
Description
In the current study, we explore coarse-grained simulations and atomistic molecular dynamics together with binding energetics scanning and cryptic pocket detection in a comparative examination of conformational landscapes and systematic