PubMed COVID-19 Clinical Care
2281 - 2290 of 5819 results found
The development of a highly sensitive and quantitative SARS-CoV-2 rapid antigen test applying newly developed monoclonal antibodies to an automated chemiluminescent flow-through membrane immunoassay device
Description
CONCLUSIONS: CoV-2-POCube has high analytical sensitivity and can detect SARS-CoV-2 variants in 15 min without observing the high-dose hook effect, thus meeting the need for early SARS-CoV-2 diagnosis with lower viral load. CoV-2-POCube is a
The evolving role of data & safety monitoring boards for real-world clinical trials
Description
CONCLUSIONS: Clinical trials can benefit from incorporating real-world data sources, potentially increasing the generalizability of findings and overall trial scale and efficiency. The data, however, present a level of informatic complexity that
TLR4 sensitizes plasmacytoid dendritic cells for antiviral response against SARS-CoV-2 coronavirus
Description
Plasmacytoid dendritic cells (pDCs) are a rare subset of dendritic cells that exhibit antiviral functions in response to toll-like receptor (TLR) 7/8 stimulations. Alternative TLRs such as TLR4 have been known to be active in pDCs for immune
The Impact of the COVID-19 Pandemic on Loneliness Among University Students: A Cross-Sectional Study in Jordan
Description
CONCLUSION: The study concluded that the frequency of loneliness was high among Jordanian university students. However, both genders experienced equal levels of loneliness, while younger participants felt more lonely than older ones.
The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes
Description
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a lipid-enveloped virus that acquires its lipid bilayer from the host cell it infects. SARS-CoV-2 can spread from cell to cell or from patient to patient by undergoing assembly and
The role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic
Description
Specific immune suppression types have been associated with a greater risk of severe COVID-19 disease and death. We analyzed data from patients >17 years that were hospitalized for COVID-19 at the "Fondazione IRCCS Ca' Granda Ospedale Maggiore
The Disruption of Patient Ambulation Care Processes by COVID-19: Revealing the Value of Visitor Assistance
Description
CONCLUSIONS: This study provides a systems-level perspective of missed ambulation during COVID-19, which revealed the value of ambulation assistance provided by visitors. Findings may be used to support the continued and increased involvement of
The Flipped Classroom Approach in a Pediatric Anesthesiology Fellowship Curriculum
Description
Background The flipped classroom approach is well documented to enhance medical education outcomes. Additionally, both the need for online learning materials and the increased demand for medical professionals during the COVID-19 pandemic has made
The causal association between polycystic ovary syndrome and susceptibility and severity of COVID-19: a bidirectional Mendelian randomization study using genetic data
Description
CONCLUSION: This MR study suggested that PCOS is not a causal risk factor for the susceptibility and severity of COVID-19. The associations identified in previous observational studies might be attributable to the presence of comorbidities in the
