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Research
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PubMed COVID-19 Clinical Care

3631 - 3640 of 4555 results found

Steeper memory decline after COVID-19 lockdown measures

Date
Saturday, April 15, 2023 - 4:00 AM
Description
CONCLUSION: Memory clinic patients, specifically in pre-dementia stages, showed faster memory decline during COVID-19 lockdown, providing evidence that lockdown regulations had a deleterious effect on brain health. In individuals that may have been

SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine receptors

Date
Saturday, April 15, 2023 - 4:00 AM
Description
Virus entry into animal cells is initiated by attachment to target macromolecules located on host cells. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) trimeric spike glycoprotein targets host angiotensin converting enzyme 2 to gain

Spatial and racial covid-19 disparities in U.S. nursing homes

Date
Saturday, April 15, 2023 - 4:00 AM
Description
In many parts of the world nursing home residents have experienced a disproportionate risk of exposure to COVID-19 and have died at much higher rates than other groups. There is a critical need to identify the factors driving COVID-19 risk in nursing

Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV)

Date
Saturday, April 15, 2023 - 4:00 AM
Description
The high morbidity and mortality associated with SARS-CoV-2 infection, the etiological agent of COVID-19, has had a major impact on global public health. Significant progress has been made in the development of an array of vaccines and biologics