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PubMed COVID-19 Clinical Care

2671 - 2680 of 2868 results found

Ribonucleic acid genome mutations induced by the Casimir effect

Date
Thursday, March 30, 2023 - 4:00 AM
Description
In this paper, we investigate the Casimir effect within a virus RNA, particularizing the study to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Then, we discuss the possibility of occurring damage or mutation in its genome due to

Rapid resistance profiling of SARS-CoV-2 protease inhibitors

Date
Thursday, March 30, 2023 - 4:00 AM
Description
Resistance to nirmatrelvir (Paxlovid) has been shown by multiple groups and may already exist in clinical SARS-CoV-2 isolates. Here a panel of SARS-CoV-2 main protease (Mpro) variants and a robust cell-based assay are used to compare the resistance