PubMed COVID-19 Clinical Care
691 - 700 of 1204 results found
New Viral Diseases and New Possible Remedies by Means of the Pharmacology of the Renin-Angiotensin System
Description
All strains of SARS-CoV-2, as well as previously described SARS-CoV and MERS-CoV, bind to ACE2, the cell membrane receptor of β-coronaviruses. Monocarboxypeptidase ACE2 activity stops upon viral entry into cells, leading to inadequate tissue
Novel siRNA therapeutics demonstrate multi-variant efficacy against SARS-CoV-2
Description
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a respiratory virus that causes COVID-19 disease, with an estimated global mortality of approximately 2%. While global response strategies, which are predominantly reliant on regular
NMR Characterization of the Papain-like Protease from SARS-CoV-2 Identifies the Conformational Heterogeneity in Its Inhibitor-Binding Site
Description
Papain-like protease (PLpro) from severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) is a prime target for the development of antivirals for Coronavirus disease 2019 (COVID-19). However, drugs that target the PLpro protein have not yet been
No Need for Parental Involvement in the Vaccination Choice of Adolescents
Description
Parental decision making is necessary for contracting medical interventions that require personal risk-benefit evaluation, and for overseeing matters of education. In the nineteenth century, exemptions from obligatory vaccination were granted for
Network-augmented compartmental models to track asymptomatic disease spread
Description
SUMMARY: A major challenge in understanding the spread of certain newly emerging viruses is the presence of asymptomatic cases. Their prevalence is hard to measure in the absence of testing tools, and yet the information is critical for tracking
Nutritional risk and clinical outcomes of COVID-19 in hospitalized children and adolescents: a multicenter cohort
Description
CONCLUSIONS: Children and adolescents with high nutritional risk by STRONGkids at hospital admission were more likely to be admitted to the ICU, have hospitalization longer than or equal to ten days, and have critical cases when infected with SARS
New-Onset Psychosis Secondary to COVID-19 Infection
Description
No abstract
New and emerging technology for adult social care - the example of home sensors with artificial intelligence (AI) technology
Description
CONCLUSIONS: This study confirmed a number of common implementation challenges, and adds insight around the specific decision-making processes for a technology that has been implemented in social care. We have also identified issues related to
