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PubMed COVID-19 Clinical Care

3041 - 3050 of 4583 results found

Immunological imprinting of humoral immunity to SARS-CoV-2 in children

Date
Thursday, June 29, 2023 - 4:00 AM
Description
Omicron variants of SARS-CoV-2 are globally dominant and infection rates are very high in children. We measure immune responses following Omicron BA.1/2 infection in children aged 6-14 years and relate this to prior and subsequent SARS-CoV-2

Immune thrombocytopenia in the setting of acute SARS-CoV-2 infection

Date
Thursday, June 29, 2023 - 4:00 AM
Description
Immune thrombocytopenia (ITP) is an immune-mediated event, characterised by the destruction of platelets by autoantibodies resulting in isolated thrombocytopaenia (platelets <100 x10⁹/L). In children, most cases are preceded by a viral infection. Cases of ITP in the setting of SARS-CoV-2 infection have been described. We describe a previously healthy boy, who presented with an extensive frontal and periorbital haematoma, petechial rash on the trunk and coryza. He had suffered a minor head...

Immunomodulatory Therapy for MIS-C

Date
Wednesday, June 28, 2023 - 4:00 AM
Description
CONCLUSIONS: In a meta-analysis of MIS-C patients, IVIG plus glucocorticoids was associated with improved CD compared with IVIG alone. Glucocorticoids alone was not associated with improved CD compared with IVIG alone or IVIG plus glucocorticoids.