A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB
Description
Myxovirus resistance proteins (MxA and MxB) are interferon-induced proteins that exert antiviral activity against a diverse range of RNA and DNA viruses. In primates, MxA has been shown to inhibit myxoviruses, bunyaviruses, and hepatitis B virus
