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PubMed COVID-19 Clinical Care

1821 - 1830 of 6604 results found

A Brief Focus on SARS-CoV-2 Genomic Evolution and Vaccines

Date
Friday, October 27, 2023 - 4:00 AM
Description
Severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) emerged in a live animal market in the Hubei Province of Wuhan in China in late 2019 and was declared a pandemic by the World Health Organization (WHO) on 11 March 2020 [...].

AntiRef: reference clusters of human antibody sequences

Date
Friday, October 27, 2023 - 4:00 AM
Description
MOTIVATION: Genetic biases in the human antibody repertoire result in publicly available antibody sequence datasets that contain many duplicate or highly similar sequences. Available datasets are further skewed by the predominance of studies focused

An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

Date
Friday, October 27, 2023 - 4:00 AM
Description
Non-structural protein 3 (nsp3) from all coronaviruses (CoVs) contains a conserved macrodomain, known as Mac1, that has been proposed as a potential therapeutic target for CoVs due to its critical role in viral pathogenesis. Mac1 is an ADP-ribose